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Coloured transmission electron micrograph (TEM) showing the limit between the oocyte (light blue) and the zona pellucida (pink). In the oocyte, the cortical granules are green. Following fertilization, the exocytosis of these granules is important to prevent polyspermy. In the zona pellucida are many microvilli of the oocyte (light blue) and one of the follicular cells (red) contacting with the oocyte surface.

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