Gout (also known as podagra when it involves the big toe) is usually characterized by recurrent attacks of inflammatory arthritis? red, tender, hot, and swollen joint. Pain typically comes on rapidly in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy.

James Gillray (13 August 1756 or 1757 ??1 June 1815) was an English caricaturist and printmaker famous for his etched political and social satires, mainly published between 1792 and 1810.