Structural 3D visualization of the spike protein 6nqd from the surface of HIV-1. This lateral view of the structure shows electrostatic charges and was visualized with Schrodinger Maestro Software. HIV-1 is one of the strains of Human Immunodeficiency Virus, the virus that causes acquired immunodeficiency syndrome (AIDS) in humans. HIV-1 spikes are targets for vaccine development to develop antibodies against them and block the virus entry into cells. Red are negative charges, blue are positive charges and gray are neutral charges.