MODEL RELEASED. Allergic reaction to an insect bite on the leg of an 8-year-old girl, causing reddening and swelling. The type of reaction to a bite or sting depends on the individual. Some people show no reaction at all, while others may suffer a potentially fatal anaphylactic shock. Treatment for the allergic response is with antihistamine drugs. Soothing creams, such as calamine, may reduce any itching.