Typhoid vaccine for U.S. soldiers. Brigadier General Frederick Fuller Russell was a U.S. Army physician who perfected a typhoid vaccine in 1909. In 1911, a typhoid vaccination program was carried out to have the entire U.S. Army immunized. As a direct result of his research, the U.S. Army was the first military to make vaccination a required prophylaxis against typhoid. The 1911 measure eliminated typhoid as a significant cause of morbidity and mortality among U.S. military personnel.