Light micrograph of an esophageal cancer biopsy (thin-section stained at h&e), specifically Infiltrating Keratinizing Well Differentiated Epidermoid Carcinoma. It is a epithelial neoplasic proliferation, constituted by epithelial cell nests, with keratin, and infiltrating in a pattern of solid nests. Esophageal cancer is a relatively rare form of cancer, of which there are several subtypes: squamous-cell cancer and adenocarcinoma. Causes: tobacco, alcohol and Barrett愀 esophagus. Treatment: surgery (esophagectomy), laser therapy (and photodynamic therapy), chemotherapy, radiotherapy, radiofrequency ablation. The prognosis is, in general, quite poor because most patients are diagnosed with an advanced stage of the disease. Field of view size: 370 x 550 痠 (0.015 x 0.022 in)