A votive relief in clay to Asclepius shaped like human intestines (3 -2nd century BC). In the Greco-Roman world, where it was believed that some gods were responsible for ill-heath. The sick and their families appealed for help to Asclepius, the most famous god of healing. His major sanctuary was at Epidaurus and in Rome was the Asklepeion Sanctuary on the island of Tiburina in the Tiber. Here there were facilities for the treatment of illnesses. The sick and their families came to the temple with their votive offerings either in gratitude or in supplication, often in the form of a small replica of a body part. Many anatomical votives have been discovered on the Tiburina island.