Cloning research. Micropipettes being used to remove the nucleus from (enucleate) a sheep oocyte cell during cloning. Oocytes from the ovaries of domestic sheep (Ovis aries) are used to clone a rare type of wild sheep called a mouflon (Ovis orientalis musimon), which lives on the islands of Sardinia and Corsica. Once the nuclear material has been removed from the sheep oocyte, it is replaced with genetic material from mouflon body (somatic) cells. The resulting cloned oocyte is cultured to the embryo stage and implanted into a foster sheep for pregnancy. The first cloned mouflon was born in October 2000 at Italy's Teramo University. Cloning may aid mouflon conservation.

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