Madonna and Child Enthroned with St John Baptist, St Francis, St Jerome, St Sebastian (Pala Buffi), by Giovanni Santi, 1489 about, 15th Century, painting on curved panel, cm 330 x 221. Italy, Marche, Pesaro Urbino, Urbino, Marche National Gallery. The painting is known as Pala Buffi from the Urbinate name of the family that commissioned it for the altar of the chapel of San Sebastiano in the church of San Francesco. The entire composition symbolize a great ex-voto. All. Madonna throne cloak crown Jesus Baby Child coral saints John Baptist cartouche Francis friar monk habit tonsure Jerome old beard Sebastian arrows wounds halos commissioners man woman Baby Child cap bonnet family floor marble background hills theory procession seraphs cherubs God Father benedictory globe sphere angels red green pink blue.